| Titre : | Emergence of Domestically acquired ceftriaxone-resistant Salmonella infections associated with AmpC bêta-lactamase. (2000) |
| Auteurs : | Eileen-F DUNNE ; Frederick-J ANGULO ; Timothy-J BARRETT ; Paul-D FEY ; B.E.N. HOLLAND ; P.A.T. KLUDT ; Corinne MILLER ; Farzad MOSTASHARI ; James-K RASHEED ; Roshan REPORTER ; Efrain-M RIBOT ; P.A.M. SHILLAM ; Karen STAMEY ; Fred-C TENOVER ; Julie WICKLUND ; Foodborne and Diarrheal Diseases Branch. Division of Bacterial and Mycotic Diseases. National Center for Infectious Diseases. Centers for Disease Control and Prevention. Atlanta. GA. USA |
| Type de document : | Article |
| Dans : | JAMA - Journal of the american medical association (vol. 284, n° 24, 2000) |
| Pagination : | 3151-3156 |
| Langues: | Anglais |
| Mots-clés : | Bactérie ; Salmonellose ; Bactériose ; Infection ; Etats Unis ; Amérique ; Surveillance ; Homme ; Médicament antibiotique ; Amérique du Nord |
| Résumé : | [BDSP. Notice produite par INIST FR0x8JWT. Diffusion soumise à autorisation]. Context Ceftriaxone, an expanded-spectrum cephalosporin, is an antimicrobial agent commonly used to treat severe Salmonella infections, especially in children. Ceftriaxone-resistant Salmonella infections have recently been reported in the United States, but the extent of the problem is unknown. Objectives To summarize national surveillance data for ceftriaxone-resistant Salmonella infections in the United States and to describe mechanisms of resistance. Design and Setting Case series and laboratory evaluation of human isolates submitted to the Centers for Disease Control and Prevention from 17 state and community health departments participating in the National Antimicrobial Resistance Monitoring System (NARMS) for enteric bacteria between 1996 and 1998. Patients Patients with ceftriaxone-resistant Salmonella infections between 1996 and 1998 were interviewed and isolates with decreased ceftriaxone susceptibility were further characterized. Main Outcome Measures Exposures and illness outcomes, mechanisms of resistance. Results The prevalence of ceftriaxone-resistant Salmonella was 0.1% (1 of 1326) in 1996,0.4% (5 of 1301) in 1997, and 0.5% (7 of 1466) in 1998. Ten (77%) of the 13 patients with ceftriaxone-resistant infections were aged 18 years or younger. The patients lived in 8 states (California, Colorado, Kansas, Massachusetts, Maryland, Minnesota, New York, and Oregon). (...) |
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